The Therapy of Ulcer

Gastric and duodenal ulcers are generally treated with several types of medicines by doctors. They advice people to reduce stress and to modify their lifestyle.When treating H.pylori the following types of medicines are used H2-blockers, proton-pump inhibitors and mucosal protective agents.So these medications are used in combination with antibiotics.When complications arise and when the medication is ineffective, surgery may be required.

The amount of acid that the stomach makes is reduced by H2-blockers. These medicines include cimetidine (Tagamet), ranitidine (Zantac), famotidine (Pepcid) and nizatidine (Axid).The stomach production of acid is modified by proton-pump inhibitors and these ones stopping the stomach acid pump, which is the final step of acid secretion.Omeprazole (Prilosec) was recently aproved and now is recognized an available drug and is ten times more powerful in suppressing stomach acid production than the H2-blockers.A stomach acid production can be suppressed by a potent acid inhibitor.It is more common for treating people whose ulcer fail to respond to H2-receptor blockers or other medications and those with Zollinger-Ellison syndrome.The lining of the stomach is protected by the mucosal protective agents.The prescribed medications are sucralfate (Sulcrate or Carafate) and misoprostol (Cytotec).The antacids such as Tums and Rolaids and bismuth subsalicylate (Pepto-Bismol) are not prescription medications.

Ulcers can be treated by a short course of combined high dose antibiotic therapy rather than acid-suppression alone.So are used two types of combined therapy: triple therapy and dual therapy.The triple therapy includes: metronidazole (Flagyl),tetracycline (Achromycin or Sumycin) and Pepto-Bismol, all taken four times a day.This therapy lasts two weeks.The treatment in destroying the H. pylori bacteria and in reducing the risk of reoccurrence is 90 percent effective.Dual therapyincludes:amoxicillin taken two to four times a day or Biaxin three times a day and Prilosec taken two times a day.It lasts two weeks and the treatment is 80 percent effective.

Vagotomy, antrectomy and pyloroplasty are the most common types of surgery for ulcers. For example vagotomy involves cutting the vagus nerve which gives messages from the brain to the stomach. The acid secretion is reduces by this interruption. Antrectomy removes the lower part of the stomach,the one which stimulates the secretion of digestive juices.So the duodenum and the small intestine is enlarged, so the contents pass more freely from the stomach.

If you need more information about ulcer you should ask your doctor and he will be certainly prepared to answer your questions.

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