Amphetamines are a group of synthetic psychoactive
When amphetamine was first synthesized in 1887, by the German chemist L. Edeleano, the stimulant effects were not noticed. In the early 1930s, when amphetamine’s CNS stimulant properties and use as a respiratory stimulant were discovered it was marketed as an inhaler for nasal congestion (Benzedrine©). Benzedrine is the trade name for the
Amphetamines may produce acute systemic effects, which includes cardiac irregularities and gastric disturbances. Chronic use frequently results in insomnia, hyperactivity, irritability, and aggressive behavior.
Abuse of amphetamine began rising during the 1960s and 1970s with the discovery that the intravenous injection of amphetamines (particularly methamphetamine) produced enhanced euphoric effects with a more rapid onset than oral administration. Amphetamine is also popular with athletes in training because of the enhanced performance consequent on increased cardiac output.
Popularly known as bennies, crank, speed, pep pills, wakeups, or uppers, amphetamines are easily addictive and abused. Users run the risk of becoming psychologically dependent on the
Addiction could end in psychosis or death from hyper-exhaustion or cardiac arrest. Amphetamine-induced psychosis shows remarkable similarity to schizophrenia, with paranoia and hallucinations.
There are no known over-the-counter