Oncocytoma – A Kidney Tumor

Oncocytomas are a kind of benign kidney tumor that at times could develop relatively large. As with renal adenomas, it at times can be hard to tell them apart from kidney cancers. Since oncocytomas do not usually extend to other organs, removing the kidney can frequently generate a cure.

Oncocytoma initially explained by Zippel in 1942. This tumor signifies a different pathologic entity. Klein and Valensi in 1976 published their case sequence of patients with oncocytoma. The authors stressed the benign course of the disease and its distinct pathologic characteristics.

The Office of Rare Diseases (ORD) of the National Institutes of Health (NIH) recorded kidney oncocytoma as “uncommon disease”. This denotes that in the US population, kidney oncocytoma or a subtype of renal oncocytoma has an effect on less than 200,000 people.

In some sequences, kidney oncocytoma represents up to 18% of all solid neoplasms measuring 4 cm or less. Because radiologic difference between a renal cell carcinoma and oncocitoma is nearly impracticable, the histologic examination represents the foundation stone of diagnosis.

Oncocytoma of the kidney typically comes out as well-encapsulated tumors. Revoltingly, in general the tumor is small but can get to a large size and has a gray-white to tan cut surface. Microscopically, the tumor is made of large eosinophilic cytoplasm which has a lot of mictochondria. These tumors ought to be distinguished from renal cell carcinoma which has granular cells.

Some of the symptoms of kidney oncocytoma incude flank pain, blood in urine, abdominal mass, and asymptomatic. Patients with acquired cystic kidney disease (ACKD) are at an augmented risk of renal neoplasms. Repeated tumors are adenomas and renal cell carcinomas. However, kidney oncocytomas can happen in patients with ACKD.