Epstein Barr Virus Treatment – Drugs and Medication

Most doctors will recommend rest and fluids for Epstein Barr virus treatment. In some cases, especially if there are complications, medical drugs may be prescribed.

Let’s have a look at the most commonly prescribed drugs for the treatment of EBV.

Pain relievers

To relieve the pain of a sore throat, headache or muscle aches, pain relievers like acetaminophen or ibuprofen may be recommended.

Aspirin should never be used in Epstein Barr virus treatment, particularly in children under the age of 16 due to its association with Reye’s syndrome – a potentially fatal inflammation of the brain and liver.


Antibiotics are of no use in treating EBV, since these drugs only target bacteria not viruses. In fact using antibiotics like ampicillin or amoxicillin can result in the appearance of a pink or red measles-like skin rash on the body.

If a serious secondary bacterial infection like bronchitis or pneumonia develops then the use of antibiotics may be warranted. Replenishing the healthy gastrointestinal flora with probiotics is recommended after the course of antibiotics has been finished.


Antivirals like acyclovir have been used in studies with conflicting results. The current advice is that acyclovir should not be used in uncomplicated cases of EBV.


Corticosteroids may be prescribed when there are serious complications like swelling of the airways, hepatitis (liver inflammation), hemolytic anemia (red blood cell destruction), severe thrombocytopenia (decreased blood platelets) or nerve or heart problems. Corticosteroids are potentially life-saving but should not be used long term because of side effects like immune suppression.

There are natural alternatives to using drugs for Epstein Barr virus treatment. Boosting the immune system with vitamins, minerals, herbs, homeopathics, a healthy diet and stress management are effective treatment options without the side effects of conventional medication.