Diabetes and the Obesity Risk Factor

There is a far tighter relationship between type2 diabetes and obesity than an interesting statistical equivalent raise. That 80% of type2 diabetes sufferers are overweight or obese suggests a strong link on its own merits. The prevalence of type2 diabetes has skyrocketed in the past 30 years, statistics revealing a somewhat similar percentage in the alarming rise of obesity during this same period.

In fact studies have proven beyond doubt that the onset of type 2 diabetes may be dramatically delayed with an active healthy lifestyle plan. The 10 million American people considered in the high risk group of people likely to develop type2 diabetes can lower their chances of becoming sufferers of typ2 diabetes with a recommended diet and exercise plan as according to the findings of a large scale clinical trial conducted by the Indiana University school of medicine and 26 other participating nationwide medical centers. The results were so comprehensive that the trial was ended early.

Subjects selected for the trial were selected from a broad spectrum of the population likely to develop diabetes. Namely people who were overweight with impaired glucose intolerance, a condition that often preceded type2 diabetes. Other subjects included individuals aged over 60, women with a history of gestational diabetes, and people with a close blood relative with type2 diabetes. Participants assigned to the lifestyle intervention plan, maintaining active physical exercise for just 30 minutes a day recorded a reduction in the likelihood of developing this disease by a staggering 58%.

Adding weight to further support the suggested link between type2 diabetes and obesity is research conducted by a team of scientists from the Pennsylvania school of medicine. The team had been investigating why a class of drugs, thiazolidinediones (TZDâEUR (TM) s) were effective in combating diabetes. The findings indicated that TZD drugs are likely to be have been successful by targeting a hormone.

Is there a link between diabetes and obesity? Recent studies suggest an answer to this pertinent question. Scientists led by Michale Lazar, at the University of Pennsylvania School of Medicine, had been examining why a class of drugs called thiazolidinediones (TZDs) can help fight diabetes. They discovered that TZDs cause the bodyâ € ™ s cells to utilize insulin more efficaciously, and this told them that the TZD drug could be targeting a hormone.

The hormone called resistin is produced is produced by fat cells in mice. This same hormone is present in humans. Speculation suggests that the hormone resistin has evolved to deal with periods of famine. When resistin levels were lowered the mice tested recovered the ability to transport glucose although their systems. Important in establishing the link between type2 diabetes and obesity was the finding the finding that high levels of resistin were present in mice obese from overeating.

Over a decade of research on diabetes has found that nutrients in the body such as glucose and fat contribute to insulin resistance.

Experts do not indicate that being overweight causes type2 diabetes, but the chances of developing the disease are more likely for overweight persons. Individuals may better prevent type2 diabetes with improved lifestyle activity and a more careful nutrition plan.