Metabolic disorders are genetic conditions where enzymes used to digest food do not function properly. They can lead to mild to severe brain damage, physical disability, organ failure and even death. Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body’s fuel. Your body can use this fuel right away, or it can store the energy in your body tissues, such as your liver, muscles and body fat.
The main features of metabolic syndrome comprise insulin resistance, hypertension (high blood pressure), cholesterol abnormalities, and an augmented risk for clotting. Patients are most often overweight or obese. Metabolic syndrome is quite common. Approximately 20%-30% of the population in industrialized countries have metabolic syndrome. Many medical conditions, genetics and the environment both play important roles in the development of the metabolic syndrome. Genetic factors influence each individual component of the syndrome, and the syndrome itself.
A family olden time that includes type 2 diabetes, hypertension, and early heart disease greatly enlarged the chance that an individual will develop the metabolic syndrome. Environmental issues such as low activity level, sedentary lifestyle, and progressive weight gain also contribute significantly to the risk of developing the metabolic syndrome. Metabolic syndrome is present in about 5% of people with normal body weight, 22% of those who are overweight and 60% of those considered obese. Adults who continue to gain five or more pounds per year raise their risk of developing metabolic syndrome by up to 45%.
Obesity is likely the greatest risk factor of metabolic disorder. Additional risk factors of metabolic disorder include smoking, eating an excessively high carbohydrate diet, lack of activity, and consuming an alcohol-free diet. The treatments for metabolic disorders vary, depending on what type of condition is involved and how severe the symptoms are. Weight reduction usually requires a specifically tailored multifaceted program that includes diet and exercise. Sometimes medications may be useful. Metformin (Glucophage), usually used to treat type 2 diabetes, also has been found to help prevent the onset of diabetes in people with metabolic syndrome.