A risk factor is something that can be observed or measured and is associated with a disease. The coronary arteries deliver blood to the heart muscle. Anything that interferes with blood delivery to the heart muscle will lead to heart muscle injury. We know that cholesterol deposits in the arteries, especially calcified deposits, are associated with disease of the coronary arteries.
The newest theory as to how inflammation occurs has to do with local fat deposits in or around internal organs. We know the liver can be injured by fatty deposits. This condition abbreviated NAFLD for non-alcoholic fatty liver disease, is caused by obesity. The rapid gaining or losing of weight can injure the liver. When too much fat is in the liver, it interferes with the livers function of detoxification of the blood.
The heart is the latest organ to be proven to be injured by excess fatty tissue packed around it. It is injured because Fat is not inert. It does store energy to be used in times of starvation, but the fat cell is an endocrine organ. It responds to being filled by producing chemicals that ought to make us not feel hungry. Once it is over filled, it ceases to function in concert with the other tissues and organs. It begins to function in a way that harms the body. Fat wrapped into thick layers around the coronary arteries secrets inflammatory chemicals that cause irritation in the lining of the arteries supplying the heart itself with blood. This inflammation can lead to poor circulation, increased stickiness of platelets in that area, and possibly a blood clot.
A blood clot in an artery is called a myocardial Infarction. It is also called a “heart attack”. Thirty percent of first heart attacks are fatal. If you are overweight, over fat and have a waist size over 40 inches for men or 36 inches for women, you need to do something about it.