Chandler’s syndrome (CS) is a rare eye disorder. Chandler’s syndrome (CS) is caused herpes. The problem is that the corneal endothelium (which lines the inside of the cornea) grows outward and over the trabecular meshwork. The problem then is that the meshwork is blocked and the pressure goes up. The cells also grow over the iris surface, which causes the strange pupillary findings and other things. Chandler syndrome, the more common of the three, manifests greater corneal changes and edema but fewer iris abnormalities. Cogan-Reese syndrome presents with iris atrophy, corneal endotheliopathy, corneal edema, and prominent iris nevi.
Patients with Chandler’s syndrome typically have worse corneal edema than the rest of the group, while secondary glaucoma is more severe in the other Chandler’s syndrome affects females more often than males. It usually presents sometime during middle age. Management of Chandler’s syndrome (CS) is case specific and should be dictated by the degree of corneal edema and severity of the secondary glaucoma. Topical aqueous suppressants are the medical mainstay for management of glaucoma secondary to Chandler’s syndromes. Medications that stimulate aqueous outflow are typically less effective and should not be used.
Also, laser trabeculoplasty is not seen as efficient. In serious cases, trabeculectomy may be needed, though there is a danger of shutdown of the sclerotomy place by the irregular membranes. With consequent surgeries required. Glaucoma postoperative embed devices may be needed for this cause. In these cases, penetrating keratoplasty may be needed to reestablish imagination, though this process will not impact abnormalities in the iris or anterior bedroom slant.